An investigation of the effects of lutein and zeaxanthin supplementation on inflammatory markers, ox
Project Reference: 03-PG-006
Commencement Date: October, 2003
Project Duration: 36 months
Age-related macular degeneration (AMD) is the leading cause of irreversible vision loss in industrialised countries. This project aimed to assess whether the carotenoids, lutein and zeaxanthin, in comparison to beta-carotene, exert effects on inflammatory markers and oxidative stress that may influence AMD development.
A randomised, double blind, placebo-controlled study in which smokers and non-smokers receive dietary supplements of lutein and zeaxanthin was carried out and various indicators of inflammatory status were monitored over a two-month period. A further study examined delivery of these carotenoids using food supplements (carrot juice for carotene and dried spinach powder for lutein and zeaxanthin).
Dr Jayne Woodside, Queen’s University Belfast
The PhD thesis is available on request and can be accessed through Queen’s University Belfast